Senescence Kit is ideal when cells in culture showed abnormalities typical of the Hayflick limit, after a long period of normal growth. The cells vary in size and shape, the cytoplasm begins to be granular with many cell inclusions and debris formed in the medium. Senescence goes with decreasing of proliferation potential, telomere shortening and impairment of cell function (i.e decrease of differentiation potential of stem cells). During senescence in mammalian cells, an endogenous lysosomal b-galactosidase is over-expressed and is accumulated within the aging cells. The presence of this b-Gal activity is a marker of aging cell population in vitro.
OZ Biosciences Cellular Senescence Kit allows visualization of ageing cells and is:
Simple and Rapid
Ready-to-use
- Economical
Sizes:
Fixing Buffer: 125 mL
10X PBS: 75 mL
Staining Buffer: 125 mL
25X Stock Solution of SA X-Gal: 4 x 1 mL
Shipping Conditions: Gel pack
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